A. Ribosome
B. Nucleus
C. Mitochondria
D. Plasma membrane.
The plasma membrane is the organelle that encapsulates the contents of the cell and plays a vital role in regulating the movement of substances in and out of the cell.
It is a selectively permeable barrier that separates the internal environment of the cell from the external environment.
Choice A is incorrect because ribosomes are organelles involved in protein synthesis, not in regulating the movement of substances in and out of the cell.
Choice B is incorrect because the nucleus is an organelle that contains the cell’s genetic material, not in regulating the movement of substances in and out of the cell.
Choice C is incorrect because mitochondria are organelles involved in energy production, not in regulating the movement of substances in and out of the cell.
Therefore, the Correct Answer is D.