A. fundus and body
B. cardia and fundus
C. body and pylorus
D. body
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a) fundus and body
- Correct: The majority of chemical digestion in the stomach occurs in the fundus and body regions. These regions contain gastric glands that secrete hydrochloric acid (HCl), pepsinogen, and mucus. Hydrochloric acid creates an acidic environment necessary for the activation of pepsinogen to pepsin, which is responsible for the digestion of proteins. Additionally, the stomach churns and mixes food with gastric juices in the fundus and body, facilitating the breakdown of food particles and the mixing of digestive enzymes with the food bolus.
b) cardia and fundus
- Incorrect: While the fundus region is involved in chemical digestion due to the presence of gastric glands, the cardia region primarily serves as the entry point of the esophagus into the stomach and does not significantly contribute to chemical digestion.
c) body and pylorus
- Incorrect: While the body region of the stomach is involved in chemical digestion, the pylorus region is primarily responsible for regulating the passage of partially digested food (chyme) into the small intestine through the pyloric sphincter. The pylorus region does not contribute significantly to chemical digestion.
d) body
- Incorrect: While the body region of the stomach is involved in chemical digestion, the majority of chemical digestion occurs in both the fundus and body regions. The body region alone does not represent the entirety of where chemical digestion occurs in the stomach.
Therefore, the Correct Answer is A.
In which part of the alimentary canal does most digestion occur?
A. stomach
B. proximal small intestine
C. distal small intestine
D. ascending colon
The Correct Answer is B.b) proximal small intestine
- Correct: Most digestion occurs in the proximal small intestine, specifically in the duodenum. The duodenum receives chyme from the stomach and plays a crucial role in digestion by mixing the chyme with digestive enzymes and bile. Digestive enzymes from the pancreas, including amylase, lipase, and proteases, break down carbohydrates, fats, and proteins, respectively, in the duodenum. Bile, produced by the liver and stored in the gallbladder, emulsifies fats to aid in their digestion and absorption.
a) stomach
- Incorrect: While digestion begins in the stomach, where proteins are broken down by pepsin and fats are emulsified to some extent by gastric lipase, the majority of digestion occurs in the small intestine, particularly in the duodenum.
c) distal small intestine
- Incorrect: The distal small intestine, including the jejunum and ileum, is primarily involved in nutrient absorption rather than digestion. Although some digestion continues in these regions, the majority of digestive processes have already occurred in the proximal small intestine.
d) ascending colon
- Incorrect: The ascending colon is part of the large intestine and is not directly involved in digestion. Its main function is to absorb water and electrolytes from the indigestible residue of food (feces) before it is excreted from the body.
Which structure is located where the esophagus penetrates the diaphragm?
A. esophageal hiatus
B. cardiac orifice
C. upper esophageal sphincter
D. lower esophageal sphincter
The Correct Answer is A.a) esophageal hiatus
- Correct: The structure located where the esophagus penetrates the diaphragm is called the esophageal hiatus. The esophagus passes through an opening in the diaphragm known as the esophageal hiatus as it descends from the thoracic cavity into the abdominal cavity. This hiatus allows the esophagus to connect the pharynx to the stomach.
b) cardiac orifice
- Incorrect: The cardiac orifice is the opening of the stomach into the esophagus. It is located at the superior portion of the stomach and is surrounded by the lower esophageal sphincter. It is not located where the esophagus penetrates the diaphragm.
c) upper esophageal sphincter
- Incorrect: The upper esophageal sphincter is a muscular ring located at the upper end of the esophagus, where it meets the pharynx. It controls the passage of food from the pharynx into the esophagus but is not located where the esophagus penetrates the diaphragm.
d) lower esophageal sphincter
- Incorrect: The lower esophageal sphincter (LES), also known as the cardiac sphincter, is a muscular ring located at the lower end of the esophagus, where it meets the stomach. It controls the passage of food from the esophagus into the stomach but is not located where the esophagus penetrates the diaphragm.
Which phase of deglutition involves contraction of the longitudinal muscle layer of the muscularis?
A. voluntary phase
B. buccal phase
C. pharyngeal phase
D. esophageal phase
The Correct Answer is A.a) voluntary phase
- Correct: The voluntary phase of deglutition (swallowing) involves the initial voluntary movement of food from the mouth into the pharynx. During this phase, the tongue pushes the food bolus backward toward the oropharynx. Contraction of the longitudinal muscle layer of the muscularis propels the food bolus into the pharynx, which is part of the voluntary control of swallowing.
b) buccal phase
- Incorrect: The buccal phase of deglutition involves the initial formation of the food bolus and its movement toward the oropharynx by the coordinated action of the tongue and muscles of the cheeks. It does not involve contraction of the longitudinal muscle layer of the muscularis.
c) pharyngeal phase
- Incorrect: The pharyngeal phase of deglutition is involuntary and occurs when the food bolus reaches the pharynx. It involves the sequential contraction of muscles in the pharyngeal wall to propel the food bolus downward toward the esophagus. The contraction of the longitudinal muscle layer of the muscularis is not a significant component of the pharyngeal phase.
d) esophageal phase
- Incorrect: The esophageal phase of deglutition involves the passage of the food bolus through the esophagus and into the stomach. Peristaltic waves of contraction and relaxation of the muscularis propels the food bolus along the length of the esophagus. The contraction of the longitudinal muscle layer of the muscularis primarily occurs during the voluntary phase of deglutition, not the esophageal phase.
Which of these statements about reflexes in the GI tract is false?
A. Short reflexes are provoked by nerves near the GI tract.
B. Short reflexes are mediated by the enteric nervous system.
C. Food that distends the stomach initiates long reflexes.
D. Long reflexes can be provoked by stimuli originating outside the GI tract.
The Correct Answer is C.c) Food that distends the stomach initiates long reflexes.
- False: This statement is false. Food that distends the stomach initiates short reflexes, not long reflexes. Short reflexes are local reflexes that are mediated by the enteric nervous system, which consists of a network of neurons within the walls of the digestive tract. When food stretches or distends the stomach, sensory neurons in the stomach wall detect this mechanical stimulus and initiate short reflexes that regulate local gastrointestinal functions, such as gastric motility and secretion.
. Parietal cells secrete ________.
A. gastrin
B. hydrochloric acid
C. pepsin
D. pepsinogen
The Correct Answer is B.b) hydrochloric acid
- Correct: Parietal cells, also known as oxyntic cells, secrete hydrochloric acid (HCl) into the stomach lumen. HCl plays a critical role in the digestive process by creating an acidic environment necessary for the activation of pepsinogen to pepsin and for the breakdown of food proteins. Parietal cells also secrete intrinsic factor, which is essential for the absorption of vitamin B12 in the small intestine.
a) gastrin
- Incorrect: Gastrin is a hormone secreted by G cells in the gastric glands of the stomach. It stimulates the secretion of gastric acid (HCl) by parietal cells and promotes gastric motility and emptying.
c) pepsin
- Incorrect: Pepsin is an enzyme that digests proteins by breaking them down into smaller peptides. Pepsin is formed from the precursor molecule pepsinogen, which is secreted by chief cells in the gastric glands. Parietal cells do not directly secrete pepsin.
d) pepsinogen
- Incorrect: Pepsinogen is the inactive precursor of pepsin. It is secreted by chief cells in the gastric glands of the stomach. Pepsinogen is activated to pepsin by the acidic environment created by hydrochloric acid secreted by parietal cells.
In the stomach:
A. muscles churn and mix the food with acids and enzymes
B. glands make 3 quarts of digestive juices each day
C. food leaves as a thick liquid called chyme
D. all of the above
The Correct Answer is D.d. all of the above
- Correct: All of the statements are true regarding the stomach:
a. muscles churn and mix the food with acids and enzymes: The stomach has muscular walls that contract and relax to mechanically churn and mix food with gastric juices, including hydrochloric acid and various enzymes (such as pepsin) that aid in the digestion of proteins.
b. glands make 3 quarts of digestive juices each day: The gastric glands in the lining of the stomach produce gastric juice, which contains hydrochloric acid, enzymes (such as pepsinogen), mucus, and intrinsic factor. These glands collectively secrete about 2 to 3 liters (quarts) of gastric juice per day.
c. food leaves as a thick liquid called chyme: After mixing with gastric juices and undergoing partial digestion in the stomach, food is transformed into a semi-liquid mixture called chyme. Chyme is then gradually released from the stomach into the small intestine for further digestion and absorption.
Therefore, all of the statements accurately describe processes that occur in the stomach.
During gastric emptying, chyme is released into the duodenum through the ________.
A. esophageal hiatus
B. pyloric antrum
C. pyloric canal
D. pyloric sphincter
The Correct Answer is C.c) pyloric sphincter
- Correct: During gastric emptying, chyme (partially digested food) is released from the stomach into the duodenum through the pyloric sphincter. The pyloric sphincter is a muscular valve located at the junction between the stomach and the duodenum. It regulates the passage of chyme from the stomach into the small intestine, allowing for controlled release and preventing backflow of intestinal contents into the stomach.
a) pyloric antrum
- Incorrect: The pyloric antrum is the lower portion of the stomach that leads into the pyloric canal. It is involved in mixing and churning food, but it does not regulate the release of chyme into the duodenum.
b) pyloric canal
- Incorrect: The pyloric canal is the narrow portion of the stomach that connects the pyloric antrum to the pyloric sphincter. It is involved in directing chyme toward the pyloric sphincter for release into the duodenum, but it is not the site of chyme release itself.
The esophageal hiatus is an opening in the diaphragm through which the esophagus passes as it descends from the thoracic cavity into the abdominal cavity. It is not directly involved in gastric emptying.
Which of these cells secrete hormones?
A. parietal cells
B. mucous neck cells
C. enteroendocrine cells
D. chief cells
The Correct Answer is C.c) enteroendocrine cells
- Correct: Enteroendocrine cells are specialized cells located in the epithelium of the gastrointestinal tract that secrete hormones. These hormones play various roles in the regulation of digestion, nutrient absorption, and other physiological processes. Examples of hormones secreted by enteroendocrine cells include gastrin, secretin, cholecystokinin (CCK), and ghrelin.
a) parietal cells
- Incorrect: Parietal cells are found in the gastric glands of the stomach and secrete hydrochloric acid (HCl) and intrinsic factor, but they do not secrete hormones.
b) mucous neck cells
- Incorrect: Mucous neck cells are found in the gastric glands of the stomach and secrete mucus, which helps protect the stomach lining from the acidic environment, but they do not secrete hormones.
d) chief cells
- Incorrect: Chief cells are found in the gastric glands of the stomach and secrete pepsinogen, the precursor to the enzyme pepsin, which plays a role in protein digestion. Chief cells do not secrete hormones.
Pancreatic juice ________.
A. deactivates bile.
B. is secreted by pancreatic islet cells.
C. buffers chyme.
D. is released into the cystic duct.
The Correct Answer is C.c) buffers chyme.
- Correct: Pancreatic juice contains bicarbonate ions, which act as buffers to neutralize the acidic chyme entering the duodenum from the stomach. This neutralization is essential for maintaining the optimal pH for the activity of digestive enzymes in the small intestine.
a) deactivates bile.
- Incorrect: Pancreatic juice does not deactivate bile. Bile is not deactivated in the digestive process; instead, it aids in the emulsification and digestion of fats in the small intestine.
b) is secreted by pancreatic islet cells.
- Incorrect: Pancreatic juice is secreted by exocrine cells called pancreatic acinar cells, not by pancreatic islet cells. Pancreatic islet cells secrete hormones such as insulin and glucagon, which regulate blood glucose levels.
d) is released into the cystic duct.
- Incorrect: Pancreatic juice is released into the duodenum through the pancreatic duct, not the cystic duct. The cystic duct connects the gallbladder to the common bile duct, allowing bile to be released into the duodenum when needed for digestion.
Which of these ingredients in saliva is responsible for activating salivary amylase?
A. mucus
B. phosphate ions
C. chloride ions
D. urea
The Correct Answer is B.b) phosphate ions
- Correct: Phosphate ions are responsible for activating salivary amylase. Saliva contains salivary amylase (also known as alpha-amylase or ptyalin), which is an enzyme that catalyzes the hydrolysis of starch into maltose and other smaller carbohydrates. However, salivary amylase is only activated in the presence of certain ions, particularly phosphate ions. These ions help to stabilize the enzyme's structure and facilitate its enzymatic activity. Therefore, phosphate ions play a crucial role in the function of salivary amylase.
a) Mucus
- Incorrect: Mucus in saliva serves primarily as a lubricant and protective barrier for the oral mucosa and facilitates swallowing. It does not directly activate salivary amylase
c) Chloride ions
- Incorrect: Chloride ions are electrolytes present in saliva, but they do not directly activate salivary amylase. Instead, they help maintain the osmotic balance and pH of saliva.
d) Urea
- Incorrect: Urea is a waste product found in urine and is not directly involved in the activation of salivary amylase.